HIV Target gene Detail Information

> MTA1 Gene Search Result

Gene Information

Gene Name	MTA1
Gene ID	9112
Gene Full Name	metastasis associated 1
Transcripts	ENSG00000182979
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q13330
HGNC ID	HGNC:7410
VEGA ID	OTTHUMG00000150362
OMIM ID	603526
String ID	9606.ENSP00000333633
PharmGKB ID	PA31218

Target gene [MTA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000754	chr14	216	30	44	290	View
4007643	chr1	8	10		18	View
4013773	chr1	1	2		3	View
4014652	chr1		2		2	View
4015193	chr1	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MTA1 expression and immune infiltrating cell level correlation result in HIV+ samples
MTA1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MTA1 expression and immune infiltrating cell level correlation result in HIV+ samples
MTA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).