HBV Target gene Detail Information

> MT1E Gene Search Result


Gene Information
Gene Name MT1E
Gene ID 4493
Gene Full Name metallothionein 1E
Gene Alias MT1; MTD; MT-1E; MT-IE
Transcripts ENSG00000169715
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID P04732
HGNC ID HGNC:7397
VEGA ID OTTHUMG00000133014
OMIM ID 156351
String ID 9606.ENSP00000307706
Drugbank ID BE0008824; BE0008688
PharmGKB ID PA31202
Target gene [MT1E] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1000213 chr16 2184 990 828 4002 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of MT1E expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
MT1E expression: Low -> High
Lollipop of MT1E expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of MT1E expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MT1E expression and immune infiltrating cell level correlation result in HBV+ samples
MT1E expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).