HIV Target gene Detail Information

> MRPS6 Gene Search Result

Gene Information

Gene Name	MRPS6
Gene ID	64968
Gene Full Name	mitochondrial ribosomal protein S6
Gene Alias	S6mt; RPMS6; MRP-S6; C21orf101
Transcripts	ENSG00000243927
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Predicted intracellular proteins, Ribosomal proteins
Uniport_ID	P82932
HGNC ID	HGNC:14051
VEGA ID	OTTHUMG00000065820
OMIM ID	611973
String ID	9606.ENSP00000382250
PharmGKB ID	PA31025

Target gene [MRPS6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011605	chr21	5	1		6	View
4013477	chr21		3		3	View
4016640	chr21				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MRPS6 expression and immune infiltrating cell level correlation result in HIV+ samples
MRPS6 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MRPS6 expression and immune infiltrating cell level correlation result in HIV+ samples
MRPS6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).