HTLV1 Target gene Detail Information

> MRPS22 Gene Search Result

Gene Information

Gene Name	MRPS22
Gene ID	56945
Gene Full Name	mitochondrial ribosomal protein S22
Gene Alias	GIBT; ODG7; GK002; C3orf5; COXPD5; RPMS22; MRP-S22
Transcripts	ENSG00000175110
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Ribosomal proteins
Uniport_ID	P82650
HGNC ID	HGNC:14508
VEGA ID	OTTHUMG00000159910
OMIM ID	605810
String ID	9606.ENSP00000418008
PharmGKB ID	PA31010

Target gene [MRPS22] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6004709	chr3	107			107	View
6016285	chr3	9	3		12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of MRPS22 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MRPS22 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of MRPS22 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MRPS22 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of MRPS22 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MRPS22 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).