HIV Target gene Detail Information

> MRPL22 Gene Search Result

Gene Information

Gene Name	MRPL22
Gene ID	29093
Gene Full Name	mitochondrial ribosomal protein L22
Gene Alias	L22mt; RPML25; HSPC158; MRP-L22; MRP-L25
Transcripts	ENSG00000082515
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Predicted intracellular proteins, Ribosomal proteins
Uniport_ID	Q9NWU5
HGNC ID	HGNC:14480
VEGA ID	OTTHUMG00000130190
OMIM ID	611835
String ID	9606.ENSP00000431040
PharmGKB ID	PA30952

Target gene [MRPL22] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006510	chr5	24			24	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MRPL22 expression and immune infiltrating cell level correlation result in HIV+ samples
MRPL22 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MRPL22 expression and immune infiltrating cell level correlation result in HIV+ samples
MRPL22 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).