HIV Target gene Detail Information

> MRPL14 Gene Search Result

Gene Information

Gene Name	MRPL14
Gene ID	64928
Gene Full Name	mitochondrial ribosomal protein L14
Gene Alias	L14mt; L32mt; MRPL32; RMPL32; RPML32; MRP-L14; MRP-L32
Transcripts	ENSG00000180992
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Predicted intracellular proteins, Ribosomal proteins
Uniport_ID	Q6P1L8
HGNC ID	HGNC:14279
VEGA ID	OTTHUMG00000014756
OMIM ID	611827
String ID	9606.ENSP00000361084
PharmGKB ID	PA30943

Target gene [MRPL14] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001059	chr6	15	115	93	223	View
4005994	chr6	28			28	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MRPL14 expression and immune infiltrating cell level correlation result in HIV+ samples
MRPL14 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MRPL14 expression and immune infiltrating cell level correlation result in HIV+ samples
MRPL14 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).