HTLV1 Target gene Detail Information

> MRC1 Gene Search Result

Gene Information

Gene Name	MRC1
Gene ID	4360
Gene Full Name	mannose receptor C-type 1
Gene Alias	MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1
Transcripts	ENSG00000260314
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins
Uniport_ID	P22897
HGNC ID	HGNC:7228
VEGA ID	OTTHUMG00000174646
OMIM ID	153618
String ID	9606.ENSP00000455897
Drugbank ID	BE0009301
PharmGKB ID	PA30933

Target gene [MRC1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6021211	chr10	6			6	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of MRC1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MRC1 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of MRC1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MRC1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).