HBV Target gene Detail Information

> MPRIP Gene Search Result


Gene Information
Gene Name MPRIP
Gene ID 23164
Gene Full Name myosin phosphatase Rho interacting protein
Gene Alias MRIP; RIP3; M-RIP; RHOIP3; p116Rip
Transcripts ENSG00000133030
Virus HBV
Gene Type protein coding
HPA Location Info Actin filaments;Cytosol;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q6WCQ1
HGNC ID HGNC:30321
VEGA ID OTTHUMG00000059276
OMIM ID 612935
String ID 9606.ENSP00000379156
PharmGKB ID PA162396092
Target gene [MPRIP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005377 chr17 29 15 13 57 View
1012976 chr17 6 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MPRIP expression and immune infiltrating cell level correlation result in HBV+ samples
MPRIP expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).