HIV Target gene Detail Information

> MPP5 Gene Search Result

Gene Information

Gene Name	MPP5
Gene ID	64398
Gene Full Name	membrane palmitoylated protein 5
Gene Alias	PALS1
Transcripts	ENSG00000072415
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Plasma membrane;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q8N3R9
VEGA ID	OTTHUMG00000171243
OMIM ID	606958
String ID	9606.ENSP00000261681
PharmGKB ID	PA38631

Target gene [MPP5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001119	chr14	158	9	44	211	View
4004675	chr14	2	39		41	View
4005909	chr14	15	8	5	28	View
4006948	chr14	1	21		22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MPP5 expression and immune infiltrating cell level correlation result in HIV+ samples
MPP5 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MPP5 expression and immune infiltrating cell level correlation result in HIV+ samples
MPP5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).