HIV Target gene Detail Information

> MPI Gene Search Result


Gene Information
Gene Name MPI
Gene ID 4351
Gene Full Name mannose phosphate isomerase
Gene Alias PMI; PMI1; CDG1B
Transcripts ENSG00000178802
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID P34949
HGNC ID HGNC:7216
VEGA ID OTTHUMG00000142826
OMIM ID 154550
String ID 9606.ENSP00000318318
PharmGKB ID PA30922
Target gene [MPI] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4008603 chr15 12 1 1 14 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of MPI expression and immune infiltrating cell level correlation result in HIV+ samples
MPI expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).