HIV Target gene Detail Information

> MPC1 Gene Search Result

Gene Information

Gene Name	MPC1
Gene ID	51660
Gene Full Name	mitochondrial pyruvate carrier 1
Gene Alias	MPYCD; BRP44L; CGI-129; SLC54A1
Transcripts	ENSG00000060762
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q9Y5U8
HGNC ID	HGNC:21606
VEGA ID	OTTHUMG00000015999
OMIM ID	614738
String ID	9606.ENSP00000354223
PharmGKB ID	PA134940737

Target gene [MPC1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4016404	chr6				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MPC1 expression and immune infiltrating cell level correlation result in HIV+ samples
MPC1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).