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HBV Target gene Detail Information

> MORF4L2 Gene Search Result


Gene Information
Gene Name MORF4L2
Gene ID 9643
Gene Full Name mortality factor 4 like 2
Gene Alias MRGX; MORFL2
Transcripts ENSG00000123562
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q15014
HGNC ID HGNC:16849
VEGA ID OTTHUMG00000022104
OMIM ID 300409
String ID 9606.ENSP00000394417
PharmGKB ID PA134925837
Target gene [MORF4L2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007362 chrX 15 13 28 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of MORF4L2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
MORF4L2 expression: Low -> High
Lollipop of MORF4L2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of MORF4L2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MORF4L2 expression and immune infiltrating cell level correlation result in HBV+ samples
MORF4L2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).