HIV Target gene Detail Information

> MORC3 Gene Search Result

Gene Information

Gene Name	MORC3
Gene ID	23515
Gene Full Name	MORC family CW-type zinc finger 3
Gene Alias	NXP2; ZCW5; ZCWCC3
Transcripts	ENSG00000159256
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Mitochondria;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q14149
HGNC ID	HGNC:23572
VEGA ID	OTTHUMG00000086620
OMIM ID	610078
String ID	9606.ENSP00000383333
PharmGKB ID	PA128394632

Target gene [MORC3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003455	chr21	56	5		61	View
4004044	chr21	40	9	1	50	View
4007115	chr21	21			21	View
4011015	chr21	5	2		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MORC3 expression and immune infiltrating cell level correlation result in HIV+ samples
MORC3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MORC3 expression and immune infiltrating cell level correlation result in HIV+ samples
MORC3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).