HTLV1 Target gene Detail Information

> MOGAT1 Gene Search Result


Gene Information
Gene Name MOGAT1
Gene ID 116255
Gene Full Name monoacylglycerol O-acyltransferase 1
Gene Alias MGAT1; DGAT2L; DGAT2L1
Transcripts ENSG00000124003
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted membrane proteins
Uniport_ID Q96PD6
HGNC ID HGNC:18210
VEGA ID OTTHUMG00000153394
OMIM ID 610268
String ID 9606.ENSP00000406674
PharmGKB ID PA27305
Target gene [MOGAT1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000727 chr2 394 275 258 927 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of MOGAT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MOGAT1 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of MOGAT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MOGAT1 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of MOGAT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MOGAT1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).