HBV Target gene Detail Information

> MMP2 Gene Search Result

Gene Information

Gene Name	MMP2
Gene ID	4313
Gene Full Name	matrix metallopeptidase 2
Gene Alias	CLG4; MONA; CLG4A; MMP-2; TBE-1; MMP-II
Transcripts	ENSG00000087245
Virus	HBV
Gene Type	protein coding
HPA Location Info	Vesicles;Predicted to be secreted;
HPA Protein Class Info	Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	P08253
HGNC ID	HGNC:7166
VEGA ID	OTTHUMG00000133202
OMIM ID	120360
String ID	9606.ENSP00000219070
Drugbank ID	BE0000642
PharmGKB ID	PA30877

Target gene [MMP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005448	chr16	54			54	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MMP2 expression and immune infiltrating cell level correlation result in HBV+ samples
MMP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).