HIV Target gene Detail Information

> MMADHC Gene Search Result

Gene Information

Gene Name	MMADHC
Gene ID	27249
Gene Full Name	metabolism of cobalamin associated D
Gene Alias	cblD; C2orf25; CL25022
Transcripts	ENSG00000168288
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q9H3L0
HGNC ID	HGNC:25221
VEGA ID	OTTHUMG00000155558
OMIM ID	611935
String ID	9606.ENSP00000389060
PharmGKB ID	PA164723053

Target gene [MMADHC] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003867	chr2	53			53	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MMADHC expression and immune infiltrating cell level correlation result in HIV+ samples
MMADHC expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MMADHC expression and immune infiltrating cell level correlation result in HIV+ samples
MMADHC expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).