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HBV Target gene Detail Information

> MMAB Gene Search Result


Gene Information
Gene Name MMAB
Gene ID 326625
Gene Full Name metabolism of cobalamin associated B
Gene Alias ATR; cob; cblB; CFAP23
Transcripts ENSG00000139428
Virus HBV
Gene Type protein coding
HPA Location Info Mitochondria;
HPA Protein Class Info Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID Q96EY8
HGNC ID HGNC:19331
VEGA ID OTTHUMG00000169255
OMIM ID 607568
String ID 9606.ENSP00000445920
Drugbank ID BE0000456
PharmGKB ID PA134864025
Target gene [MMAB] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1100101 chr12 904 446 429 1779 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of MMAB expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
MMAB expression: Low -> High
Lollipop of MMAB expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of MMAB expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MMAB expression and immune infiltrating cell level correlation result in HBV+ samples
MMAB expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).