HBV Target gene Detail Information

> MLLT11 Gene Search Result


Gene Information
Gene Name MLLT11
Gene ID 10962
Gene Full Name MLLT11, transcription factor 7 cofactor
Gene Alias AF1Q
Transcripts ENSG00000213190
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Predicted intracellular proteins
Gene Function Oncogene
Uniport_ID Q13015
HGNC ID HGNC:16997
VEGA ID OTTHUMG00000035160
OMIM ID 604684
String ID 9606.ENSP00000357917
PharmGKB ID PA142671347
Target gene [MLLT11] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1001527 chr1 444 87 113 644 View
1400436 chr1 55 12 3 70 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MLLT11 expression and immune infiltrating cell level correlation result in HBV+ samples
MLLT11 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).