HIV Target gene Detail Information

> MLF2 Gene Search Result

Gene Information

Gene Name	MLF2
Gene ID	8079
Gene Full Name	myeloid leukemia factor 2
Gene Alias	NTN4
Transcripts	ENSG00000089693
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q15773
HGNC ID	HGNC:7126
VEGA ID	OTTHUMG00000168717
OMIM ID	601401
String ID	9606.ENSP00000203630
PharmGKB ID	PA30844

Target gene [MLF2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001520	chr12	142	12		154	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MLF2 expression and immune infiltrating cell level correlation result in HIV+ samples
MLF2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MLF2 expression and immune infiltrating cell level correlation result in HIV+ samples
MLF2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).