HBV Target gene Detail Information

> MICAL3 Gene Search Result


Gene Information
Gene Name MICAL3
Gene ID 57553
Gene Full Name microtubule associated monooxygenase, calponin and LIM domain containing 3
Gene Alias MICAL-3
Transcripts ENSG00000243156
Virus HBV
Gene Type protein coding
HPA Location Info Midbody ring;Nucleoplasm;Cytosol;Plasma membrane;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID Q7RTP6
HGNC ID HGNC:24694
VEGA ID OTTHUMG00000150067
OMIM ID 608882
String ID 9606.ENSP00000416015
PharmGKB ID PA142671454
Target gene [MICAL3] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1004996 chr22 60 4 64 View
1007891 chr22 14 9 23 View
1008669 chr22 17 3 20 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MICAL3 expression and immune infiltrating cell level correlation result in HBV+ samples
MICAL3 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).