HIV Target gene Detail Information

> MICA Gene Search Result

Gene Information

Gene Name	MICA
Gene ID	100507436
Gene Full Name	MHC class I polypeptide-related sequence A
Gene Alias	MIC-A; PERB11.1
Transcripts	ENSG00000233051
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
HGNC ID	HGNC:7090
VEGA ID	OTTHUMG00000149951
OMIM ID	600169
String ID	9606.ENSP00000413079
Rfam ID	RF00078
PharmGKB ID	PA30811

Target gene [MICA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009162	chr6	11	1		12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MICA expression and immune infiltrating cell level correlation result in HIV+ samples
MICA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).