HIV Target gene Detail Information

> MIB1 Gene Search Result

Gene Information

Gene Name	MIB1
Gene ID	57534
Gene Full Name	mindbomb E3 ubiquitin protein ligase 1
Gene Alias	MIB; DIP1; ZZZ6; DIP-1; LVNC7; ZZANK2
Transcripts	ENSG00000101752
Virus	HIV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Vesicles;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q86YT6
HGNC ID	HGNC:21086
VEGA ID	OTTHUMG00000131753
OMIM ID	608677
String ID	9606.ENSP00000261537
PharmGKB ID	PA134862722

Target gene [MIB1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009743	chr18	11			11	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MIB1 expression and immune infiltrating cell level correlation result in HIV+ samples
MIB1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MIB1 expression and immune infiltrating cell level correlation result in HIV+ samples
MIB1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).