HIV Target gene Detail Information

> MIA3 Gene Search Result

Gene Information

Gene Name	MIA3
Gene ID	375056
Gene Full Name	MIA SH3 domain ER export factor 3
Gene Alias	ARNT; D320; TANGO; TANGO1; UNQ6077
Transcripts	ENSG00000154305
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Uniport_ID	Q5JRA6
HGNC ID	HGNC:24008
VEGA ID	OTTHUMG00000037543
OMIM ID	613455
String ID	9606.ENSP00000340900
PharmGKB ID	PA143485536

Target gene [MIA3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005473	chr1	31	1		32	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MIA3 expression and immune infiltrating cell level correlation result in HIV+ samples
MIA3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MIA3 expression and immune infiltrating cell level correlation result in HIV+ samples
MIA3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).