HBV Target gene Detail Information

> MGAT5 Gene Search Result


Gene Information
Gene Name MGAT5
Gene ID 4249
Gene Full Name alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
Gene Alias GNT-V; GNT-VA; MGAT5A
Transcripts ENSG00000152127
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted membrane proteins
Uniport_ID Q09328
HGNC ID HGNC:7049
VEGA ID OTTHUMG00000131681
OMIM ID 601774
String ID 9606.ENSP00000386377
PharmGKB ID PA30784
Target gene [MGAT5] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008463 chr2 2 7 11 20 View
1018387 chr2 0 View
1400548 chr2 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MGAT5 expression and immune infiltrating cell level correlation result in HBV+ samples
MGAT5 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).