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HTLV1 Target gene Detail Information

> MGAT1 Gene Search Result


Gene Information
Gene Name MGAT1
Gene ID 4245
Gene Full Name mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
Gene Alias GnTI; MGAT; GLCT1; GLYT1; GNT-1; GNT-I; GLCNAC-TI
Transcripts ENSG00000131446
Virus HTLV1
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P26572
HGNC ID HGNC:7044
VEGA ID OTTHUMG00000130937
OMIM ID 160995
String ID 9606.ENSP00000404718
Drugbank ID BE0004519
PharmGKB ID PA30779
Target gene [MGAT1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000081 chr5 2246 1672 1257 5175 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of MGAT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MGAT1 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of MGAT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MGAT1 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of MGAT1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MGAT1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).