HIV Target gene Detail Information

> MGA Gene Search Result

Gene Information

Gene Name	MGA
Gene ID	23269
Gene Full Name	MGA, MAX dimerization protein
Gene Alias	MAD5; MXD5
Transcripts	ENSG00000174197
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Cancer-related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID	Q8IWI9
HGNC ID	HGNC:14010
VEGA ID	OTTHUMG00000172719
OMIM ID	616061
String ID	9606.ENSP00000219905
PharmGKB ID	PA134976336

Target gene [MGA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005589	chr15	27	4		31	View
4005784	chr15	28	1		29	View
4008044	chr15	2	12	2	16	View
4008048	chr15	2	12	2	16	View
4009224	chr15	5	2	5	12	View
4009326	chr15	5	7		12	View
4009442	chr15	8	3		11	View
4011444	chr15	6	1		7	View
4011533	chr15	1	5		6	View
4011706	chr15	6			6	View
4012454	chr15	5			5	View
4012455	chr15		5		5	View
4013289	chr15	1	3		4	View
4013290	chr15	2	2		4	View
4013788	chr15	3			3	View
4015281	chr15	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MGA expression and immune infiltrating cell level correlation result in HIV+ samples
MGA expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MGA expression and immune infiltrating cell level correlation result in HIV+ samples
MGA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).