HBV Target gene Detail Information

> MFSD2A Gene Search Result

Gene Information

Gene Name	MFSD2A
Gene ID	84879
Gene Full Name	major facilitator superfamily domain containing 2A
Gene Alias	NLS1; MFSD2; MCPH15
Transcripts	ENSG00000168389
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Cytoplasmic bodies;Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters
Gene Function	Suppressor gene
Uniport_ID	Q8NA29
HGNC ID	HGNC:25897
VEGA ID	OTTHUMG00000009293
OMIM ID	614397
String ID	9606.ENSP00000361895
PharmGKB ID	PA165751549

Target gene [MFSD2A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002877	chr1	62	87	47	196	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MFSD2A expression and immune infiltrating cell level correlation result in HBV+ samples
MFSD2A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).