HIV Target gene Detail Information

> MFN1 Gene Search Result

Gene Information

Gene Name	MFN1
Gene ID	55669
Gene Full Name	mitofusin 1
Gene Alias	hfzo1; hfzo2
Transcripts	ENSG00000171109
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
HGNC ID	HGNC:18262
VEGA ID	OTTHUMG00000157385
OMIM ID	608506
String ID	9606.ENSP00000420617
PharmGKB ID	PA134945973

Target gene [MFN1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003359	chr3	45	18		63	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MFN1 expression and immune infiltrating cell level correlation result in HIV+ samples
MFN1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MFN1 expression and immune infiltrating cell level correlation result in HIV+ samples
MFN1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).