HIV Target gene Detail Information

> MEX3C Gene Search Result

Gene Information

Gene Name	MEX3C
Gene ID	51320
Gene Full Name	mex-3 RNA binding family member C
Gene Alias	RKHD2; BM-013; MEX-3C; RNF194
Transcripts	ENSG00000176624
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q5U5Q3
HGNC ID	HGNC:28040
VEGA ID	OTTHUMG00000132693
OMIM ID	611005
String ID	9606.ENSP00000385610
PharmGKB ID	PA162395821

Target gene [MEX3C] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001062	chr18	151	71		222	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MEX3C expression and immune infiltrating cell level correlation result in HIV+ samples
MEX3C expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MEX3C expression and immune infiltrating cell level correlation result in HIV+ samples
MEX3C expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).