HIV Target gene Detail Information

> METTL9 Gene Search Result

Gene Information

Gene Name	METTL9
Gene ID	51108
Gene Full Name	methyltransferase like 9
Gene Alias	DREV; PAP1; DREV1; CGI-81
Transcripts	ENSG00000284548
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cell Junctions;Nucleoplasm;Cytosol;Predicted to be secreted;
HPA Protein Class Info	Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID	Q9H1A3
HGNC ID	HGNC:24586
VEGA ID	OTTHUMG00000131584
OMIM ID	609388
String ID	9606.ENSP00000350874
PharmGKB ID	PA145148428

Target gene [METTL9] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002307	chr16	30	45	25	100	View
4009059	chr16	10	2	1	13	View
4010158	chr16	9			9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of METTL9 expression and immune infiltrating cell level correlation result in HIV+ samples
METTL9 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of METTL9 expression and immune infiltrating cell level correlation result in HIV+ samples
METTL9 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).