HIV Target gene Detail Information

> METTL23 Gene Search Result

Gene Information

Gene Name	METTL23
Gene ID	124512
Gene Full Name	methyltransferase like 23
Gene Alias	MRT44; C17orf95
Transcripts	ENSG00000181038
Virus	HIV
Gene Type	protein coding
HPA Location Info	Vesicles;
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins
Uniport_ID	Q86XA0
HGNC ID	HGNC:26988
VEGA ID	OTTHUMG00000180371
OMIM ID	615262
String ID	9606.ENSP00000482599
PharmGKB ID	PA162378566

Target gene [METTL23] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006920	chr17	12	10		22	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of METTL23 expression and immune infiltrating cell level correlation result in HIV+ samples
METTL23 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).