XMRV Target gene Detail Information

> MET Gene Search Result


Gene Information
Gene Name MET
Gene ID 4233
Gene Full Name MET proto-oncogene, receptor tyrosine kinase
Gene Alias HGFR; AUTS9; RCCP2; c-Met; DFNB97
Transcripts ENSG00000105976
Virus XMRV
Gene Type protein coding
HPA Location Info Cytosol;Plasma membrane;Predicted to be secreted;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins
Gene Function Oncogene
Uniport_ID P08581
HGNC ID HGNC:7029
VEGA ID OTTHUMG00000023299
OMIM ID 164860
String ID 9606.ENSP00000317272
Drugbank ID BE0000915
Drug (Cytoscape Annotation) Axitinib;Crizotinib
PharmGKB ID PA30763
FDA Approved Drug Cabozantinib;Crizotinib;Capmatinib
Target gene [MET] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
8100022 chr7 2585 1864 1027 5476 View

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).