HPV Target gene Detail Information

> MEOX1 Gene Search Result


Gene Information
Gene Name MEOX1
Gene ID 4222
Gene Full Name mesenchyme homeobox 1
Gene Alias KFS2; MOX1
Transcripts ENSG00000005102
Virus HPV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytokinetic bridge;Cytosol;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins, Transcription factors
Uniport_ID P50221
HGNC ID HGNC:7013
VEGA ID OTTHUMG00000170513
OMIM ID 600147
String ID 9606.ENSP00000321684
PharmGKB ID PA30747
Target gene [MEOX1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5402558 chr17 6 2 8 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of MEOX1 expression and immune infiltrating cell level correlation result in HPV+ samples
MEOX1 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of MEOX1 expression and immune infiltrating cell level correlation result in HPV+ samples
MEOX1 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of MEOX1 expression and immune infiltrating cell level correlation result in HPV+ samples
MEOX1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).