HIV Target gene Detail Information

> MEGF8 Gene Search Result

Gene Information

Gene Name	MEGF8
Gene ID	1954
Gene Full Name	multiple EGF like domains 8
Gene Alias	SBP1; CRPT2; EGFL4; C19orf49
Transcripts	ENSG00000105429
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q7Z7M0
HGNC ID	HGNC:3233
VEGA ID	OTTHUMG00000150342
OMIM ID	604267
String ID	9606.ENSP00000251268
PharmGKB ID	PA27666

Target gene [MEGF8] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001471	chr19	37	105	18	160	View
4008952	chr19	12	1		13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MEGF8 expression and immune infiltrating cell level correlation result in HIV+ samples
MEGF8 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).