HIV Target gene Detail Information

> MED27 Gene Search Result

Gene Information

Gene Name	MED27
Gene ID	9442
Gene Full Name	mediator complex subunit 27
Gene Alias	MED3; CRSP8; CRAP34; CRSP34; TRAP37
Transcripts	ENSG00000160563
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoli;Nucleoplasm;Cytosol;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6P2C8
HGNC ID	HGNC:2377
VEGA ID	OTTHUMG00000020833
OMIM ID	605044
String ID	9606.ENSP00000292035
PharmGKB ID	PA162395634

Target gene [MED27] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010985	chr9	8			8	View
4012613	chr9	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MED27 expression and immune infiltrating cell level correlation result in HIV+ samples
MED27 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MED27 expression and immune infiltrating cell level correlation result in HIV+ samples
MED27 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).