HTLV1 Target gene Detail Information

> MED17 Gene Search Result

Gene Information

Gene Name	MED17
Gene ID	9440
Gene Full Name	mediator complex subunit 17
Gene Alias	SRB4; CRSP6; CRSP77; DRIP80; TRAP80
Transcripts	ENSG00000042429
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q9NVC6
HGNC ID	HGNC:2375
VEGA ID	OTTHUMG00000167497
OMIM ID	603810
String ID	9606.ENSP00000251871
PharmGKB ID	PA162395443

Target gene [MED17] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6028249	chr11	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of MED17 expression and immune infiltrating cell level correlation result in HTLV1+ samples
MED17 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).