HBV Target gene Detail Information

> MED13 Gene Search Result


Gene Information
Gene Name MED13
Gene ID 9969
Gene Full Name mediator complex subunit 13
Gene Alias ARC250; THRAP1; DRIP250; HSPC221; TRAP240
Transcripts ENSG00000108510
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins
Uniport_ID Q9UHV7
HGNC ID HGNC:22474
VEGA ID OTTHUMG00000179251
OMIM ID 603808
String ID 9606.ENSP00000380888
PharmGKB ID PA162395168
Target gene [MED13] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1012947 chr17 3 3 6 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MED13 expression and immune infiltrating cell level correlation result in HBV+ samples
MED13 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).