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HBV Target gene Detail Information

> MECP2 Gene Search Result


Gene Information
Gene Name MECP2
Gene ID 4204
Gene Full Name methyl-CpG binding protein 2
Gene Alias RS; RTS; RTT; PPMX; MRX16; MRX79; MRXSL; AUTSX3; MRXS13
Transcripts ENSG00000169057
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Predicted intracellular proteins
Uniport_ID P51608
HGNC ID HGNC:6990
VEGA ID OTTHUMG00000024229
OMIM ID 300005
String ID 9606.ENSP00000395535
PharmGKB ID PA30729
Target gene [MECP2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1003323 chrX 144 144 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE114783 (GEO) Chronic HBV (CHB) infection 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Hepatocellular carcinoma 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
GSE114783 (GEO) Liver cirrhosis 36 Chronic hepatitis B patients (HBV+)(10),Hepatocellular carcinoma (HBV+)(10),Liver cirrhosis(HBV+)(10),Normal(3),HBV carriers (3)
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: GSE114783

HeatMap of cell type fractions in all samples Lollipop of MECP2 expression and immune infiltrating cell level correlation result in HBV+ Chronic HBV (CHB) infection samples
MECP2 expression: Low -> High
Lollipop of MECP2 expression and immune infiltrating cell level correlation result in HBV+ Liver cirrhosis samples Lollipop of MECP2 expression and immune infiltrating cell level correlation result in HBV+ Hepatocellular carcinoma samples

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MECP2 expression and immune infiltrating cell level correlation result in HBV+ samples
MECP2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).