HIV Target gene Detail Information

> MEA1 Gene Search Result


Gene Information
Gene Name MEA1
Gene ID 4201
Gene Full Name male-enhanced antigen 1
Gene Alias HYS; MEA
Transcripts ENSG00000124733
Virus HIV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q16626
HGNC ID HGNC:6986
VEGA ID OTTHUMG00000014717
OMIM ID 143170
String ID 9606.ENSP00000244711
PharmGKB ID PA30726
Target gene [MEA1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000678 chr6 239 60 21 320 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of MEA1 expression and immune infiltrating cell level correlation result in HIV+ samples
MEA1 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of MEA1 expression and immune infiltrating cell level correlation result in HIV+ samples
MEA1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).