HIV Target gene Detail Information

> MCU Gene Search Result

Gene Information

Gene Name	MCU
Gene ID	90550
Gene Full Name	mitochondrial calcium uniporter
Gene Alias	HsMCU; C10orf42; CCDC109A
Transcripts	ENSG00000156026
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q8NE86
HGNC ID	HGNC:23526
VEGA ID	OTTHUMG00000018443
OMIM ID	614197
String ID	9606.ENSP00000362144
PharmGKB ID	PA134888841

Target gene [MCU] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010171	chr10	8	1		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MCU expression and immune infiltrating cell level correlation result in HIV+ samples
MCU expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).