HIV Target gene Detail Information

> MCTP2 Gene Search Result

Gene Information

Gene Name	MCTP2
Gene ID	55784
Gene Full Name	multiple C2 and transmembrane domain containing 2
Transcripts	ENSG00000140563
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q6DN12
HGNC ID	HGNC:25636
VEGA ID	OTTHUMG00000171751
OMIM ID	616297
String ID	9606.ENSP00000350377
PharmGKB ID	PA142671473

Target gene [MCTP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4005556	chr15	30	1		31	View
4011366	chr15		6	1	7	View
4012459	chr15	1	4		5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MCTP2 expression and immune infiltrating cell level correlation result in HIV+ samples
MCTP2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MCTP2 expression and immune infiltrating cell level correlation result in HIV+ samples
MCTP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).