HIV Target gene Detail Information

> MCTP1 Gene Search Result

Gene Information

Gene Name	MCTP1
Gene ID	79772
Gene Full Name	multiple C2 and transmembrane domain containing 1
Transcripts	ENSG00000175471
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q6DN14
HGNC ID	HGNC:26183
VEGA ID	OTTHUMG00000162742
OMIM ID	616296
String ID	9606.ENSP00000424126
PharmGKB ID	PA142671472

Target gene [MCTP1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008782	chr5	3	6	5	14	View
4300013	chr5	38			38	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MCTP1 expression and immune infiltrating cell level correlation result in HIV+ samples
MCTP1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MCTP1 expression and immune infiltrating cell level correlation result in HIV+ samples
MCTP1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).