HIV Target gene Detail Information

> MCM9 Gene Search Result

Gene Information

Gene Name	MCM9
Gene ID	254394
Gene Full Name	minichromosome maintenance 9 homologous recombination repair factor
Gene Alias	ODG4; MCMDC1; C6orf61; dJ329L24.1; dJ329L24.3
Transcripts	ENSG00000111877
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	Q9NXL9
HGNC ID	HGNC:21484
VEGA ID	OTTHUMG00000015468
OMIM ID	610098
String ID	9606.ENSP00000314505
PharmGKB ID	PA162395071

Target gene [MCM9] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013335	chr6	1	2	1	4	View
4016777	chr6				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MCM9 expression and immune infiltrating cell level correlation result in HIV+ samples
MCM9 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).