HPV Target gene Detail Information

> MCHR1 Gene Search Result


Gene Information
Gene Name MCHR1
Gene ID 2847
Gene Full Name melanin concentrating hormone receptor 1
Gene Alias SLC1; GPR24; MCH1R; SLC-1; MCH-1R
Transcripts ENSG00000128285
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info G-protein coupled receptors, Predicted membrane proteins, Transporters
Uniport_ID Q99705
HGNC ID HGNC:4479
VEGA ID OTTHUMG00000150256
OMIM ID 601751
String ID 9606.ENSP00000249016
Drugbank ID BE0003478
PharmGKB ID PA28867
Target gene [MCHR1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5401201 chr22 220 172 63 455 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of MCHR1 expression and immune infiltrating cell level correlation result in HPV+ samples
MCHR1 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of MCHR1 expression and immune infiltrating cell level correlation result in HPV+ samples
MCHR1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).