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HBV Target gene Detail Information

> MBL2 Gene Search Result


Gene Information
Gene Name MBL2
Gene ID 4153
Gene Full Name mannose binding lectin 2
Gene Alias MBL; MBP; MBP1; MBPD; MBL2D; MBP-C; COLEC1; HSMBPC
Transcripts ENSG00000165471
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Plasma proteins, Predicted secreted proteins
Uniport_ID P11226
HGNC ID HGNC:6922
VEGA ID OTTHUMG00000150270
OMIM ID 154545
String ID 9606.ENSP00000363079
Drugbank ID BE0004482
PharmGKB ID PA30665
Target gene [MBL2] related to virus gene/protein/region
ID PMID Mutation Gene/Protein/Region Description Detail
1 27824315 A1499G
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S
C
 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MBL2 expression and immune infiltrating cell level correlation result in HBV+ samples
MBL2 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).