HIV Target gene Detail Information

> MAVS Gene Search Result

Gene Information

Gene Name	MAVS
Gene ID	57506
Gene Full Name	mitochondrial antiviral signaling protein
Gene Alias	IPS1; VISA; IPS-1; CARDIF
Transcripts	ENSG00000088888
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q7Z434
HGNC ID	HGNC:29233
VEGA ID	OTTHUMG00000031765
OMIM ID	609676
String ID	9606.ENSP00000401980
PharmGKB ID	PA164722208

Target gene [MAVS] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4001901	chr20	49	55	18	122	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MAVS expression and immune infiltrating cell level correlation result in HIV+ samples
MAVS expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).