HBV Target gene Detail Information

> MAT2B Gene Search Result

Gene Information

Gene Name	MAT2B
Gene ID	27430
Gene Full Name	methionine adenosyltransferase 2B
Gene Alias	TGR; MAT-II; SDR23E1; MATIIbeta; Nbla02999
Transcripts	ENSG00000038274
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q9NZL9
HGNC ID	HGNC:6905
VEGA ID	OTTHUMG00000130379
OMIM ID	605527
String ID	9606.ENSP00000325425
Drugbank ID	BE0002178
PharmGKB ID	PA30648

Target gene [MAT2B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1007189	chr5	29			29	View
1007190	chr5	29			29	View
1403114	chr5	29			29	View
1403115	chr5	29			29	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MAT2B expression and immune infiltrating cell level correlation result in HBV+ samples
MAT2B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).