HBV Target gene Detail Information

> MAT1A Gene Search Result

Gene Information

Gene Name	MAT1A
Gene ID	4143
Gene Full Name	methionine adenosyltransferase 1A
Gene Alias	MAT; SAMS; MATA1; SAMS1
Transcripts	ENSG00000151224
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q00266
HGNC ID	HGNC:6903
VEGA ID	OTTHUMG00000018613
OMIM ID	610550
String ID	9606.ENSP00000361287
Drugbank ID	BE0000407
PharmGKB ID	PA30646

Target gene [MAT1A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1002807	chr10	18	173	12	203	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of MAT1A expression and immune infiltrating cell level correlation result in HBV+ samples
MAT1A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).