HBV Target gene Detail Information

> MAST4 Gene Search Result


Gene Information
Gene Name MAST4
Gene ID 375449
Gene Full Name microtubule associated serine/threonine kinase family member 4
Transcripts ENSG00000069020
Virus HBV
Gene Type protein coding
HPA Location Info Cytosol;Nucleoplasm;
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID O15021
HGNC ID HGNC:19037
VEGA ID OTTHUMG00000152471
OMIM ID 618002
String ID 9606.ENSP00000385727
PharmGKB ID PA134920494
Target gene [MAST4] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1007020 chr5 12 19 31 View
1008819 chr5 19 19 View
1009134 chr5 17 17 View
1400075 chr5 17 3 20 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of MAST4 expression and immune infiltrating cell level correlation result in HBV+ samples
MAST4 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).