HIV Target gene Detail Information

> MAST3 Gene Search Result

Gene Information

Gene Name	MAST3
Gene ID	23031
Gene Full Name	microtubule associated serine/threonine kinase 3
Transcripts	ENSG00000099308
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	O60307
HGNC ID	HGNC:19036
VEGA ID	OTTHUMG00000183418
OMIM ID	612258
String ID	9606.ENSP00000262811
PharmGKB ID	PA134877725

Target gene [MAST3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002924	chr19	68	2		70	View
4003978	chr19	19	9	23	51	View
4005526	chr19	27	4		31	View
4007975	chr19	14	3		17	View
4015647	chr19	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of MAST3 expression and immune infiltrating cell level correlation result in HIV+ samples
MAST3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of MAST3 expression and immune infiltrating cell level correlation result in HIV+ samples
MAST3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).